Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1995-06-05
1998-09-22
Fleisher, Mindy
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4352401, 4352402, 4353201, 424 932, 424 9321, 536 231, 536 245, C12N 510, C12N 1586
Patent
active
058112758
ABSTRACT:
This invention provides an infectious retrovirus having inserted between the 5' and 3' long terminal repeat sequences of the retrovirus a nucleic acid encoding an anti-HIV-type specific agent under the control of a pol III promoter. Host cells containing the retroviral vectors of this invention also are provided. Further provided are methods of interfering with or preventing HIV viral replication in a cell infected with HIV or likely to be infected with HIV.
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Ho Anthony
Leavitt Mark
Ojwang Joshua O.
Wong-Staal Flossie
Yamada Osamu
Fleisher Mindy
Railey II Johnny F.
The Regents of the University of California
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