HIV reverse transcriptase

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514414, 514418, 544144, 548484, A61K 3140, A61K 31535

Patent

active

051243270

ABSTRACT:
Novel indole compounds inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds or pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

REFERENCES:
patent: 4873259 (1989-10-01), Summers, Jr. et al.
Lyle et al., J. Med. Chem., vol. 34 (1991) pp. 1228-1230.

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