Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-03-29
1997-07-08
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544277, 544350, 544362, A61K 31495, A61K 3152, C07D40706, C07D491048
Patent
active
056461488
ABSTRACT:
Compounds of formula ##STR1## are HIV protease inhibitors. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
REFERENCES:
patent: 5413999 (1995-05-01), Vacca et al.
patent: 5502060 (1996-03-01), Thompson et al.
Kageyama et al, Antimicrobial Agents and Chemothrapy 36 pp. 926-933 (1992).
Dorsey Bruce D.
Huff Joel R.
Vacca Joseph P.
Appollina Mary A.
Bernhardt Emily
Merck & Co. , Inc.
Winokur Melvin
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