Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-05-07
1995-05-09
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514252, 514255, 514311, 544357, 544360, 544362, 544367, 544370, 544372, 544374, 544400, 546164, A61K 31495, C07D24102
Patent
active
054139996
ABSTRACT:
Compounds of formula ##STR1## where R.sup.1 and R.sup.2 are independently hydrogen or optionally-substituted C.sub.1-4 alkyl or aryl, or R.sup.1 and R.sup.2 are joined together to form a monocyclic or bicyclic ring system, are HIV protease inhibitors. These compounds are useful in the treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of treating infection by HIV are also described.
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Dorsey Bruce D.
Guare James P.
Holloway M. Katharine
Hungate Randall W.
Levin Rhonda B.
Caruso Charles M.
Merck & Co. , Inc.
Meredith Roy D.
Peabody John
Quagliato Carol S.
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