Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-06-07
1999-01-12
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514211, 514212, 514215, 514218, 540450, 540480, 540483, 540484, 540544, 540553, 540596, 540607, A61K 31395, A61K 3155, C07D26702, C07D22304
Patent
active
058590021
ABSTRACT:
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
REFERENCES:
patent: 5063208 (1991-11-01), Rosenberg et al.
patent: 5142056 (1992-08-01), Kempe et al.
patent: 5157041 (1992-10-01), Handa et al.
patent: 5196438 (1993-03-01), Martin et al.
patent: 5204471 (1993-04-01), Negele et al.
patent: 5235039 (1993-08-01), Heath, Jr. et al.
Tam et al., J. Med. Chem., 35(7): 1318-1320 (1992).
Huff, J. Med. Chem., 34(8):2305-2314 (1991).
Ghosh et al., J. Med. Chem., 36(2) :292-294 (1993).
Ghosh et al., J. Med. Chem., 36(16) :2300-2310 (1993).
Thompson et al., J. Am. Chem. Soc., 115(2) :801-802 (1993).
Rich et al., J. Med. Chem., 34(3) :1222-1225 (1991).
Thaisvivongs et al., J. Med. Chem., 34:2344-2356 (1991).
Ghosh et al., J. Med. Chem., 36:924-927 (1993).
Chong et al., J. Med. Chem., 36:2575-2577 (1993).
Vava Pradad et al., Peptides, Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium, Jun. 16-21, pp. 721-722 (1991).
Rich, et al., Chem. Abstracts, 114(15) Abstract No. 143998q (1991).
Houpis et al., Tetrahedron Letters, 34(16) :2593-2596 (1993).
Roberts, N.A. et al., Science, 248:358-361 (1990).
Gilbert et al., J. Chem. Soc. Perkin Trans., 2:475-479 (1993).
Young et al., J. Med. Chem., 35:1702-1709 (1992).
Lyle et al., J. Med. Chem., 34:1228-1230 (1991).
Kalish Vincent J.
Reich Siegfried H.
Rodriguez Michael J.
Tatlock John H.
Agouron Pharmaceuticals , Inc.
M. Mach D. Margaret
Rotman Alan L.
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