Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-05-17
1997-05-06
Jordan, Charles T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A01N 4300, A61K 31395
Patent
active
H00016497
ABSTRACT:
Combinations of certain HIV-1 protease inhibitors are provided which effectively inhibit the HIV-1 protease enzyme while eliminating or substantially reducing the viral cross-resistance seen with use of individual HIV-1 protease inhibitors. Such combinations are useful in the treatment of diseases associated with the AIDS virus.
REFERENCES:
patent: 5484926 (1996-01-01), Dressman et al.
HIV-1 Protease Inhibitors: Their Development, Mechanism of Action and Clinical Potential, D. Pillay et al, Rev. Med. Virol., 5: 23-33, 1995.
D. pillay et al., "HIV-1 Protease Inhibitors: . . . Clin. Potential", Rev. Med. Virol., vol. 5, pp. 23-33.
Barrish Joel C.
Colonno Richard J.
Lin Pin-Fang M.
Chelliah Meena
Jordan Charles T.
Morse David M.
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