HIV nuclear localization inhibitors

Details HIV nuclear localization inhibitors HIV nuclear localization inhibitors

1997-08-15

1998-09-15

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544298, 514269, 514274, C07D23924, A61K 31495

Patent

active

058080686

ABSTRACT:
There is disclosed a genus of compounds that have anti-HIV infection therapeutic activity and inhibit nuclear localization of the HIV preintegration complex.

REFERENCES:
Popov et al., Proc. Natl. Acad. Sci. USA, vol. 93, pp. 11859-11864, 1996.
Dubrovsky et al., Molcular Medicine, vol. 1, No. 2, pp. 217230, 1995.

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