HIV integrase inhibitors: cyclic pyrimidinone compounds

Details HIV integrase inhibitors: cyclic pyrimidinone compounds HIV integrase inhibitors: cyclic pyrimidinone compounds

2005-11-14

2008-09-02

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

C514S211120, C514S267000, C514S230200, C544S230000, C544S070000, C544S071000, C540S542000, C540S543000

Reexamination Certificate

active

07419969

ABSTRACT:
The invention encompasses a series of pyrimidinone compounds which inhibit HIV integrase and thereby prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses intermediates useful for making the pyrimidone compounds. Additionally, pharmaceutical compositions and methods for treating those infected with HIV are encompassed.

REFERENCES:
patent: 2004/0006065 (2004-01-01), Giunz
patent: WO 03/035076 (2003-05-01), None
patent: WO 03/035077 (2003-05-01), None
patent: WO 2004/058756 (2004-07-01), None
patent: WO 2004/058757 (2004-07-01), None
patent: WO 2005/061490 (2005-07-01), None
patent: WO 2005/061501 (2005-07-01), None
patent: WO 2005/070901 (2005-08-01), None
U.S. Appl. No. 10/755,642, filed Jan. 12, 2004, Michael A. Walker et al.

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