HIV integrase inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S277000

Reexamination Certificate

active

07619086

ABSTRACT:
Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication:wherein Z, R1, R2, R3, R4, R5, R6, R7, R8and R9are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

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