Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-03-04
2009-11-17
Krass, Frederick (Department: 1612)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S277000
Reexamination Certificate
active
07619086
ABSTRACT:
Compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication:wherein Z, R1, R2, R3, R4, R5, R6, R7, R8and R9are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
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Fisher Thorsten E.
Lyle Terry A.
Morrissette Matthew M.
Wai John S.
Williams Peter D.
Heber Sheldon O.
Krass Frederick
Merck & Co. , Inc.
Sznaidman Marcos
Walton Kenneth R.
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