HIV integrase inhibitors

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using fungi

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544360, 549267, 514450, A61K 3135, C07D31178, C07D32110

Patent

active

061107166

ABSTRACT:
Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

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