HIV capsid assembly-associated compositions and method

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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C435S005000

Reexamination Certificate

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07348134

ABSTRACT:
A cell-free method for translation and assembly of retroviral, particularly HIV, capsid and capsid intermediates is disclosed. Also disclosed are novel HIV capsid assembly intermediates and novel host proteins which bind to such assembly intermediates. The invention also includes a screening method for compounds that alter retrovirus capsid assembly, and a method of treating HIV using compounds which inhibit the HIV capsid assembly pathway.

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