Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1994-03-15
1999-02-23
Smith, Lynette F.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530395, 435 71, 435 5, 435 721, C07K 100, C07K 1400, C07K 1700, G01N 3353
Patent
active
058745335
ABSTRACT:
Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
REFERENCES:
patent: 4569794 (1986-02-01), Smith et al.
patent: 4812556 (1989-03-01), Vahine et al.
patent: 4925784 (1990-05-01), Crowl et al.
Kyte and Doolittle, J. Mol. Biol. 157:105-132 (1982) "A Simple Method for Displaying the Hhydropathic Character of a Protein".
Pauletti, et al., Anal. Biochem. 151:540-546 (1985) "Application of a Modified Computer Algorithm in Determining Potential Antigenic Determinants Asso. with the . . . ".
Hopp and Woods, Proc. Natl. Acid. Sci. 78(6):3824-3828 (1981) "Prediction of Protein Antigentic Determinants from Amino Acid Sequences".
Clavel, et al., Science 233:343-346 (1986) "Isolation of a New Human Retrovirus for West African Patients with AIDS".
Clavel, et al., Nature 324:691-69 (1986) "Molecular Cloning and Polymorphism of the Human Immune Deficiency Virus Type 2".
Guyader, et al., Nature 326:662-669 (1987) "Genome Organization and Transactivation of the Human Immunodeficiency Virus Type 2".
Brun-Vezinet, et al., Lancet 1:128-132 (1987) "Lymphadenopathy--Asso. Virus Type 2 in AIDS and AIDS-related complex".
Hochuli, et al., Biol. Chem. Hoppe-Seyler 368:748 (1987) "Alpha-alkyl Nitrilotriacetic Acid Adsorbants . . . ".
Villarejo, et al., J. Bacteriol. 120:466-474 (1974) "Beta Galactosidase from Termination and Deletion Mutant Strains".
Certa, et al., EMBO J.5(11):3051-3056 (1986) "Subregions of a Conserved Part of the HIV . . . ".
Shoeman, et al., Anal. Biochem. 161:370-379 (1987) "Comparison of Recombinant Human Immunodeficiency . . . ".
Cordonnier, et al, 1989, "Single Amino-acid changes in HIV envelope . . . " Nature 340:571-574.
Pongor, 1987, "The Use of Structural Profiles . . . " Methods in Enzymology 154:450-473.
Bannwarth Wilhelm
Caspers Patrick
Le Grice Stuart
Mous Jan
Johnson George W.
Rocha-Tramaloni Patricia S.
Roche Diagnostic Systems, Inc.
Smith Lynette F.
LandOfFree
HIV-2 envelope polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with HIV-2 envelope polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and HIV-2 envelope polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-308096