Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1995-05-15
1998-08-11
Scheiner, Laurie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
4242081, 435 5, 435 71, A61K 3921, C12Q 170, G01N 3353
Patent
active
057924597
ABSTRACT:
HIV-1 envelope muteins are provided comprising deletions within the hypervariable domains of the polypeptides. Methods of using these proteins in immunoassay and to elicit antibody production are also disclosed, as well as materials and methods useful for producing the muteins by recombinant DNA technology.
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Blackburn Robert P.
Chiron Corporation
Harbin Alisa A.
Hoscheit Dale H.
Parkin Jeffrey S.
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