Histone deacetylase inhibitors

Details Histone deacetylase inhibitors Histone deacetylase inhibitors

2007-01-30

2007-01-30

Lambkin, Deborah C. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S339000, C546S210000, C548S309700

Reexamination Certificate

active

10803344

ABSTRACT:
Compounds that may be used to inhibit histone deacetylase having the formulain-line-formulae description="In-line Formulae" end="lead"?Z-Q-L-M or Z-L-Min-line-formulae description="In-line Formulae" end="tail"?wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0–10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.

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