Histone deacetylase inhibitors

Details Histone deacetylase inhibitors Histone deacetylase inhibitors

2008-05-20

2008-05-20

Chang, Celia (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07375228

ABSTRACT:
Compounds that may be used to inhibit histone deacetylase having the formulain-line-formulae description="In-line Formulae" end="lead"?Z-Q-L-M or Z-L-Min-line-formulae description="In-line Formulae" end="tail"?wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.

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