Histone deacetylase inhibitors

Details Histone deacetylase inhibitors Histone deacetylase inhibitors

2005-07-08

2010-06-15

Anderson, Rebecca L (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C564S123000

Reexamination Certificate

active

07737184

ABSTRACT:
This invention relates to hydroxamic acid derivatives having a urea linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.

REFERENCES:
patent: 5369108 (1994-11-01), Breslow et al.
patent: 5700811 (1997-12-01), Breslow et al.
patent: 5932616 (1999-08-01), Breslow et al.
patent: 6087367 (2000-07-01), Breslow et al.
patent: 6511990 (2003-01-01), Breslow et al.
patent: 6620828 (2003-09-01), Chu et al.
patent: 2004/0077635 (2004-04-01), Qiao et al.
Vippagunta, et al Advanced Drug Delivery Reviews. 48 (2001) 3-26.
Cancer and Metastasis Reviews (1998), 17(1), 91-106.
Science (1999), vol. 286, 531-537.
Cancer [online], [retrieved on Jul. 6, 2007], Retrieved from the internet, URL; http://www.nlm.nih.gov/medlineplus/cancer.html>.
Cancer [online], [retrieved on Jul. 7, 2007], retrieved from the initernet, URL; http://en.wikipedia.org/wiki/Cancer>.
Bauer, et al., Biorganic and Medicinal Chemistry Letters, vol. 14(15), pp. 4045-4050 (2004).

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