Histone deacetylase as target for antiprotozoal agents

Details Histone deacetylase as target for antiprotozoal agents Histone deacetylase as target for antiprotozoal agents

1999-11-18

2000-05-30

Achutamurthy, Ponnathapu

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 692, 435195, 4352523, 514449, 514895, C12Q 134, C12N 1509, C12N 914, H01N 4302

Patent

active

060689870

ABSTRACT:
Histone deacetylase inhibition provides a target for identifying potential antiprotozoal compounds. Histone deacetylase inhibitors are useful as therapeutic agents against protozoal infections.

REFERENCES:
patent: 4218478 (1980-08-01), Omura et al.
patent: 5356927 (1994-10-01), Taraschi et al.
Lechner, et al., Biochem, et Biophysica Acta, vol. 1926, No. 2, pp. 181-188 (1996).
Brosch, et al., The Plant Cell, vol. 7, No. 11, pp. 1941-1950 (1995).
Kervabon, et al., Febs Letters, vol. 106, No. 1, pp. 93-96 (1979).
Bioassays, 17(5): p. 423 (1995).
J. Biol. Chem. 268(30): p. 22429 (1993).
J. Antibiot., 43(12): p. 1524 (1990).
Acta Cryst. C., 47: p. 1469 (1991).
Jap. J. Cancer Res., 83(4): p. 324 (1992).
J. Med. Chem., 30: p. 71 (1987).
Experientia, 41: p. 348 (1985).
Biochimie, 71: p. 71 (1989).
Tet. Lett., 35(33): p. 6009 (1994).
Biochem., 22: p. 3507 (1983).
J. Med. Chem., 24: p. 567 (1981).
Amino Acids, 6(3): p. 315 (1994).
Biochem., 22: p. 3502 (1983).
Eur. J. Cancer, 10:801 (1974).
Phytopathology, 57: p. 1169 (1967).
Biochem. Biophys. Res. Comm. 107:785 (1982).
Bioch J., 1994, 303: pp. 723-729.
J. Biol. Chem., 1990, 265:17174.

Affiliated with

Also associated with

Rating

Histone deacetylase as target for antiprotozoal agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Histone deacetylase as target for antiprotozoal agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Histone deacetylase as target for antiprotozoal agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1909283