Histone deacetylase as target for antiprotozoal agents

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 18, 435 692, 424 941, 514895, C12Q 148, A61K 3843

Patent

active

061106976

ABSTRACT:
Histone deacetylase inhibition provides a target for identifying potential antiprotozoal compounds. Histone deacetylase inhibitors are useful as therapeutic agents against protozoal infections.

REFERENCES:
patent: 4218478 (1980-08-01), Omura et al.
patent: 5356927 (1994-10-01), Taraschi et al.
patent: 5620953 (1997-04-01), Cannova et al.
Lechner, et al, Biochim. et Biophysica Acta, vol. 1926, No. 2, pp 181-188 (1996).
Brosch, et al, The Plant Cell, vol. 7, No. 11, pp 1941-1950 (1995).
Kervabon, et al, Febs Letters, vol. 106, No. 1, pp. 93-96 (1979).
Yoshida, et al., J. Biol. Chem., vol. 265, pp. 17174-17179, 1990.
Yoshida, et al., J. Antibiotics, vol. 43, pp. 1101-1106, 1990.
Bioassays, 17(5): p. 423, 1995.
J. Biol. Chem. 268(30): p. 22429, 1993.
J. Antibiot., 43(12): p. 1524, 1990.
Acta Cryst. C, 47: p.1469, 1991.
Jap. J. Cancer Res., 83(4): p. 324, 1992.
J. Med. Chem., 30: p. 71, 1987.
Experientia, 41: p. 348, 1985.
Biochimie, 71: p. 71, 1989.
Tet. Lett., 35(33): p. 6009, 1994.
Biochem., 22: p. 3507, 1983.
J. Med. Chem., 24: p. 567, 1981.
Amino Acids, 6(3): p. 315, 1994.
Biochem., 22: p. 3502, 1983.
Eur. J. Cancer, 10:801, 1974.
Phytopathology, 57: p. 1169, 1967.
Biochem. Biophys. Res. Comm. 107:785, 1982.
Bioch J., 1994, 303: 723-729.
J. Biol. Chem., 1990, 265:17174.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Histone deacetylase as target for antiprotozoal agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Histone deacetylase as target for antiprotozoal agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Histone deacetylase as target for antiprotozoal agents will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1248514

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.