Histidine and homohistidine derivatives as inhibitors of protein

Details Histidine and homohistidine derivatives as inhibitors of protein Histidine and homohistidine derivatives as inhibitors of protein

1994-06-30

1996-11-05

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 514 94, 514311, 514399, 546146, 548111, 5483381, 530331, A61K 31415, C07D23364, C07K 5078, C07K 5097

Patent

active

055717926

ABSTRACT:
Novel inhibitors of protein farnesyltransferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

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