Histamine H.sub.1 antagonists

Details Histamine H.sub.1 antagonists Histamine H.sub.1 antagonists

1986-09-24

1987-12-29

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544268, 544269, C07D47308, A61K 3152

Patent

active

047161655

ABSTRACT:
Histamine H.sub.1 antagonists of the formula: ##STR1## in which R.sup.1 is hydrogen or alkyl of 1 to 6 carbon atoms; ##STR2## and the other is hydrogen or alkyl of 1 to 6 carbon atoms, where ##STR3## in which X is hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, halo, cyano or a nitro substituent on one of the available carbon atoms; and

REFERENCES:
patent: 4426383 (1984-01-01), Sugimoto et al.
patent: 4493837 (1985-01-01), Sugimoto et al.
patent: 4603204 (1986-07-01), Thiele et al.

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