Histamine derivative, process for preparing it and its therapeut

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514397, C07D23364, A61K 31415

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active

050345397

ABSTRACT:
The present invention relates to .alpha.,.beta.-dimethylhistamine, of the rmula: ##STR1## in racemic form, or an optical isomer form or mixture of diastereoisomers and its acid addition salts. It may be prepared from an alkyl 2-amino 3-(1H-imidazol-4-yl)-carboxylate.

REFERENCES:
patent: 4767778 (1988-08-01), Arrang et al.
Chemical Abstracts 85(5):28472; Durant et al. (1976).
Arch. Pharm (Weinheim) 313; 709-714 (1980) Gerhard et al.
Frontiers in Histamine Research (1985), pp. 39-46, Ganellin et al.

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