Histamine antagonist, an interleukin-1 antagonist and/or a TNF a

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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Details

424701, 514840, 514859, 514937, 514944, A61K 748

Patent

active

056585810

ABSTRACT:
The invention relates to the use of a histamine antagonist, an interleukin-1 antagonist and/or a TNF alpha anlagonist in a cosmetic, pharmaceutical or dermatological composition for treating sensitive skins. It relates especially to the use of a histamine antagonist, an interleukin-1 antagonist and/or a TNF alpha antagonist for preventing and/or combating skin irritations and/or sores and/or erythema and/or dysaesthetic sensations and/or sensations of inflammation and/or pruritus and/or prickling and/or tingling and/or discomfort and/or tightness of the skin and/or mucosae. It also relates to a composition containing a histamine antagonist, an interleukin-1 anlagonist and/or a TNF alpha antagonist which limits or eliminates the irritant side-effects of certain products, and in particular of certain cosmetic, dermatological or pharmaceutical active agents.

REFERENCES:
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patent: 4808612 (1989-02-01), Skotnicki et al.
patent: 4902685 (1990-02-01), Skotnicki
patent: 4902800 (1990-02-01), Skotnicki
patent: 5002941 (1991-03-01), Adams et al.
patent: 5281608 (1994-01-01), Skotnicki et al.
Japanese Patent Abstracts, Publication No. JP4089428, publication date Mar. 23, 1992.
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Japanese Patent Abstracts, Publication No. JP1238509, publication date Sep. 22, 1989.
The Merck Index, Eleventh Edition, Published by Merck & Co., Inc., Rahway, N.J. pp. 940 and 9623, (1989).
The Year's Drug News by Joseph R. Prous, pp. 186-187 (1994).

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