Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-11-22
1995-07-04
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549354, 435 41, 435 53, A61K 3134, C07D30700
Patent
active
054300509
ABSTRACT:
The compound of formula, ##STR1## is obtained from cultures of Chaetosphaeronema hispidulum. The compound is an inhibitor of phospholipase C.
REFERENCES:
Nordlander, J. E., et al., Journal of Organic Chemistry, vol. 49, No. 1, pp. 133-138 (1984).
Sechi, A. M., et al., Archives of Biochemistry and Biophysics, vol. 186, No. 2, pp. 248-254, Mar. 1978.
Ohtsuka Tatsuo
Okuda Toru
Sakai Akiko
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Rotman Alan L.
Semionow Raina
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