His-Gly-Gly peptide and derivatives thereof for hair growth

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530331, A61K 3702, C07K 508

Patent

active

052525597

ABSTRACT:
The present invention relates to a composition for regulating hair growth comprising a safe and effective amount of the tripeptide histidyl-glycyl-glycine, or a derivative thereof, and a pharmaceutically-acceptable carrier.

REFERENCES:
patent: 4665054 (1987-05-01), Pickart
patent: 4760051 (1988-07-01), Pickart
Bachem Bioscience, Inc., Catalog US 4--1991 p. 295.
Ueda, J., A., Hanaki, N. Yoshida and T. Nakajima-".sup.1 H-Nuclear Magnetic Resonance Study of the Interaction of Zinc(II) Ion with a Histidine-Containing Peptide, L-Histidylglycylglycine," Chem. Pharm. Bull. vol. 33, pp. 3096-3100 (1985).
Yokoyama, A., H. Aiba and H. Tanaka-"Acid Dissociation Constants of Some Histidine-Containing Peptides and Formation Constants of Thier Metal Complexes," Bulletin of the Chemical Society of Japan, vol. 47, pp. 112-117 (1974).
Schneider, F.-"Tripeptide des Histidins," Z. Physiol. Chem., vol. 321, pp. 38-48 (1960).
Davis, N. C.-"Action of Proteolytic Enzymes on Some Peptides and Derivatives Containing Histidine," J. Bio. Chem., vol. 223, pp. 935-947 (1956).

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