Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-06-05
1996-07-23
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 21, 530324, 530350, 530402, A61K 3800, C07K 300, C07K 500, C07K 700
Patent
active
055389465
ABSTRACT:
The present invention relates to hirudin derivatives which are formed from hirudin or the physiologically acceptable salt thereof and a carrier, to a process for the preparation thereof, and to the use thereof as thrombin inhibitor.
REFERENCES:
patent: 4703039 (1987-10-01), Hawiger et al.
patent: 4791100 (1988-12-01), Kramer et al.
The Merck Index, Eleventh Edition, 1989, Susan Budavari, Editor, pp. THER-11 and THER-28.
Torchilin et al., Annals of the New York Academy of Sciences, vol. 501, 1987, pp. 481-486.
Richter et al., Die Pharmazie, vol. 44, Jan. 1989, pp. 73-74.
Lehninger. Biochemistry. 1970, pp. 266, 272, and 273.
Spinner et al., "Quantitative enzyme-linked immunosorbent assay (ELISA) for hirudin", Journal of Immunological Methods, vol. 87 (1986), pp. 79-83.
Veronese et al., "Surface Modification of Proteins, Activation of Monomethoxy-Polyethylene Glycols by Phenylchloroformates and Modification of Ribonuclease and Superoxide Dismutase", Applied Biochemistry and Biotechnology, vol. 11, (1985), pp. 141-152.
P. Walsmann et al., "Biochemische und pharmakologische Aspekte des Thrombininhibitors Hirudin", Die Pharmazie, 1981, pp. 653-659.
Daniel Bagdy et al, "Hirudin," Naturally Occurring Protease Inhibitors, vol. 54, pp. 669-678.
John W. Fenton, II et al., "Thrombin Active-Site Regions," Seminars in Thrombosis and Hemostasis, vol. 12, No. 3, 1986, pp. 200-208.
Wallace et al., Biochemistry, vol. 28, pp. 10079-10084 (1989).
Crause Peter
Habermann Paul
Kramer Martin
Obermeier Rainer
Sauber Klaus
Chan Christina Y.
Davenport A. M.
Hoechst Aktiengesellschaft
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