Hirudin derivatives with delayed action

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 21, 530324, 530350, 530402, A61K 3800, C07K 300, C07K 500, C07K 700

Patent

active

055389465

ABSTRACT:
The present invention relates to hirudin derivatives which are formed from hirudin or the physiologically acceptable salt thereof and a carrier, to a process for the preparation thereof, and to the use thereof as thrombin inhibitor.

REFERENCES:
patent: 4703039 (1987-10-01), Hawiger et al.
patent: 4791100 (1988-12-01), Kramer et al.
The Merck Index, Eleventh Edition, 1989, Susan Budavari, Editor, pp. THER-11 and THER-28.
Torchilin et al., Annals of the New York Academy of Sciences, vol. 501, 1987, pp. 481-486.
Richter et al., Die Pharmazie, vol. 44, Jan. 1989, pp. 73-74.
Lehninger. Biochemistry. 1970, pp. 266, 272, and 273.
Spinner et al., "Quantitative enzyme-linked immunosorbent assay (ELISA) for hirudin", Journal of Immunological Methods, vol. 87 (1986), pp. 79-83.
Veronese et al., "Surface Modification of Proteins, Activation of Monomethoxy-Polyethylene Glycols by Phenylchloroformates and Modification of Ribonuclease and Superoxide Dismutase", Applied Biochemistry and Biotechnology, vol. 11, (1985), pp. 141-152.
P. Walsmann et al., "Biochemische und pharmakologische Aspekte des Thrombininhibitors Hirudin", Die Pharmazie, 1981, pp. 653-659.
Daniel Bagdy et al, "Hirudin," Naturally Occurring Protease Inhibitors, vol. 54, pp. 669-678.
John W. Fenton, II et al., "Thrombin Active-Site Regions," Seminars in Thrombosis and Hemostasis, vol. 12, No. 3, 1986, pp. 200-208.
Wallace et al., Biochemistry, vol. 28, pp. 10079-10084 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hirudin derivatives with delayed action does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hirudin derivatives with delayed action, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hirudin derivatives with delayed action will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-713065

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.