Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1997-04-21
1999-11-02
Carlson, Karen Cochrane
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435 691, 536 231, 536 243, 536 232, C12N 902, C12P 2106, C07H 1700
Patent
active
059768509
ABSTRACT:
This invention provides novel hippocampus-associated proteins and DNA sequences coding therefor. In an investigation of hippocampus-associated proteins by differential screening of a rat hippocampus cDNA library, a cDNA species encoding a novel protein designated Hct-1 was isolated and shown to be a to cytochromes P450. The use of hybridization probes based on the rat Hct-1 sequence has led to the identification of homologues in other mammalian species.
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Volk. "Mapping of phenytoin-inducible cytochrome p450 . . . " Neuroscience, vol. 42 No. 1, 1991, pp. 215-235.
Anandatheerthavarada et al. "Rat brain cytochromes P-450 . . . " Brain Res., vol. 536 No. 1-2, Dec. 1990, pp. 339-343.
Stryer et al. 1981. Biochemistry 2nd Ed. W.H. Freeman and Company, San Francisco pp. 629.
Lathe Richard
Rose Kenneth Andrew
Stapleton Genevieve
Carlson Karen Cochrane
University of Edinburgh
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