Hindered linking agents derived from 2-iminothiolanes and method

Details Hindered linking agents derived from 2-iminothiolanes and method Hindered linking agents derived from 2-iminothiolanes and method

1989-12-21

1992-03-03

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530345, 530370, 530395, 530396, 530404, 530408, 424 8591, 435188, 546284, 549 57, 549 60, 549 68, C07K 1706, C07D33336, A61K 3944

Patent

active

050934759

ABSTRACT:
Novel compounds and methods for the formation of disulfide linkages are presented. The novel compounds employed are substituted 2-iminothiolane hydrohalide linking agents of the following formula (I): ##STR1## wherein, X is halogen;

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