Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2011-02-08
2011-11-29
Nashed, Nashaat (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
08067541
ABSTRACT:
Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99° C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80° C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins.
Bradbury Andrew M.
Kiss Csaba
Waldo Geoffrey S.
Cottrell Bruce H.
Los Alamos National Security LLC
Nashed Nashaat
Schoenfeld Meredith H.
LandOfFree
Highly thermostable fluorescent proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Highly thermostable fluorescent proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Highly thermostable fluorescent proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4255319