Highly stable surface plasmon resonance plates, microarrays,...

Details Highly stable surface plasmon resonance plates, microarrays,... Highly stable surface plasmon resonance plates, microarrays,...

2005-12-06

2008-12-09

Zimmer, Marc S (Department: 1796)

Optics: measuring and testing

Of light reflection

C356S448000, C435S287700, C435S287800, C435S288700, C428S446000, C428S447000, C428S450000, C428S615000, C428S621000, C428S624000, C428S629000, C428S630000, C428S668000

Reexamination Certificate

active

07463358

ABSTRACT:
An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.

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Machine translation of DE 10064146.
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