Highly pure acarbose

Details Highly pure acarbose Highly pure acarbose

1986-12-11

1990-02-27

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 308, A61K 3170

Patent

active

049047698

ABSTRACT:
A purified acarbose which contains less than 10% by weight of sugar-like secondary components is obtained by column chromatograph of a solution of prepurified acarbose with a pH 4 to 7. The column contains as a packing material a weakly acid cation exchanger which has carboxyl groups and is based on dextran, agarose and cellulose or exchangers which are derived from the latter with the addition of polyamide.

REFERENCES:
patent: 4062950 (1977-12-01), Frommer
patent: 4174439 (1979-11-01), Rauenbusch
patent: 4526784 (1985-07-01), Heiker
patent: 4536493 (1985-08-01), Junge
patent: 4666776 (1987-06-01), Lange

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