Highly packed polycationic ammonium, sulfonium and phosphonium l

Details Highly packed polycationic ammonium, sulfonium and phosphonium l Highly packed polycationic ammonium, sulfonium and phosphonium l

1997-01-13

1998-11-10

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424 121, 424450, 435829, 514 2, 514 19, 514 77, 514170, 514171, 564509, 564511, 564512, A61K 3113, C07C21113

Patent

active

058344390

ABSTRACT:
The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Methods for their preparation and use as intracellular delivery agents are also disclosed.

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