High yield process for preparing beta-lactam antibiotics having

Details High yield process for preparing beta-lactam antibiotics having High yield process for preparing beta-lactam antibiotics having

1985-06-03

1986-11-25

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540215, 540317, C07D50104, C07D50106, C07D49912

Patent

active

046250212

ABSTRACT:
A high yield process for preparing beta-lactam antibiotics having a high purity degree, in particular derivatives of the cephalosporanic and penicillanic acids, of the formula: ##STR1## by condensation of the compounds ##STR2## where X.dbd.H --OCH.sub.3 (suitably blocked), with a chloride of the formula ##STR3## wherein R.dbd.H, OH in which said condensation is carried out in the presence of a nicotinic or isonicotinic base.

REFERENCES:
patent: 3963704 (1976-06-01), Ferres

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