Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-07-19
2000-10-03
Jordan, Charles T.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C12P 2106
Patent
active
H00018929
ABSTRACT:
This invention describes how to make and use several effective high volume screens for the discovery of inhibitors of specific protein:protein interactions, using aspects of the yeast two-hybrid system.
REFERENCES:
patent: 4833080 (1989-05-01), Brent
patent: 5079143 (1992-01-01), Klein
patent: 5283173 (1994-02-01), Fields
patent: 5468614 (1995-11-01), Fields et al.
patent: 5525490 (1996-06-01), Erickson et al.
patent: 5539085 (1996-07-01), Bischoff et al.
patent: 5610015 (1997-03-01), Wickens et al.
Mendelsohn et al. 1994, vol. 5, No. 5, pp. 482-486, Oct. 1994.
Sikorski et al. 1991. Methods of Enzymology, vol. 194, pp. 302-318, 1991.
Fields, S., et al., 1994, Trends in Genetics, vol. 10, No. 8, pp. 286-292, Aug. 1994.
Chien, C.-T., Proc. Natl. Acad. Sci. , USA, 88:9578-82 (1991).
Allen, G. C., Jr., J. Biol. Chem., 266:22096-22101 (1991).
Arai, K.I., J. Biol. Chem., 256:5281-5286 (1981).
Bartel, P. L., In: Cellular Interactions and Development: A Practical Approach, pp. 153-179 (1993a).
Bartel, P., BioTechniques, 14:920-924 (1993b).
Brent, R., Cell, 43:729-736 (1985).
Coghlan, V.M., et al., Science, 267:108-111 (1995).
Durfee, T. K., et al., Genes and Dev., 7:555-569.
Elledge, S. J., et al., Proc. Natl. Acad. Sci. USA, 88:1731-1735 (1991).
Feilotter, H. E., et al., Nucleic Acids Res., 22:1502-1503 (1994).
Fields, S., et al., Trends in Genetics, 10:286-292 (1994).
Fields, S., et al., Nature, 340:245-246 (1989).
Finely, R. L., et al., Proc. Natl. Acad. Sci. USA, 91:12980-12984 (1994).
Golemis, E. A., et al., Molec. Cell. Biol., 12;3006-3014 (1992).
Hiasa, H., et al., J. Biol. Chem. 267:11379-11385 (1992).
Harper, J. W., et al., Cell, 75:805-816 (1993).
Helps, N. R., et al., FEBS Lett., 340:93-98 (1994).
Hill, C. W., et al., Proc. Natl. Acad. Sci. USA, 78:7069-7072 (1982).
Hoeffler, J.P., et al., J. Cell. Biochem., Suppl. 18D, 190 (1994).
Johnson, M., et al., Molec. Cell. Biol., 4, pp. 1440-1448 (1984).
Kalpana, G.V., et al., Science, 266, pp. 2002-2006 (1994).
Keegan, L., et al., Science, 231, pp. 699-704 (1986).
Klein, R. D. et al., Curr. Genet.13, pp. 29-35 (1989a).
Klein, R. D. et al., Curr. Genet., 16, pp. 145-152 (1989b).
Klopotowski, T. et al., Arch. Biochem. Biophys., 112, pp. 562-566 (1965).
LeDouarin, B. et al., Nucleic Acids Res., 23, 5, pp. 876-878 (1995).
Li, B. et al., FASEB J., 7, pp. 957-963 (1993).
Lorch, Y. et al., J. Mol. Biol., 186, pp. 821-824 (1984).
Luban, J. et al., Cell, 73, pp. 1067-1078 (1993).
Ma, J. et al., Cell, 48, pp. 847-853 (1987).
Marszalek, J. et al., J. Biol. Chem., 269, pp. 4883-4890 (1994).
Morin, P. J. et al., Nucleic Acids Res., 21, pp. 2157-2163 (1993).
Paetkau, D. W. et al., Genes and Dev., 8, pp. 2035-2045 (1994).
Sato, T. et al., Proc. Natl. Acad. Sci. USA., 91, pp. 9238-9242 (1994).
Spaargaren, M. et al., Proc. Natl. Acad. Sci. USA., 91, 12609-12613 (1994).
Stukenberg, P. T. et al, Cell, 78, pp. 877-887 (1994).
Tougu, K. et al., J. Biol. Chem., 269, pp. 4675-4682 (1994).
Vojtek, A. B. et al., Cell, 74, pp. 205-214 (1993).
Wickner, S. et al., Proc. Natl. Acad. Sci. USA, 72, pp. 921-925 (1975).
Yang, M. et al., Nuc. Acids Res., 23, 7, pp. 1152-1156 (1995).
Ye, Z. S. et al., Proc. Natl. Acad. Sci. USA, 91, pp. 12629-12633 (1994).
Yeung, K. C. et al., Genes and Dev., 8, pp. 2097-2109 (1994).
Zang, X-F. et al., Nature, 364, pp. 308-313 (1993).
Buysse Jerry M.
Klein Ronald D.
Chelliah Meena
Jordan Charles T.
Pharmacia and Upjohn Company
Wootton Thomas A.
LandOfFree
High volume nutrient based yeast two-hybrid assay for the identi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with High volume nutrient based yeast two-hybrid assay for the identi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High volume nutrient based yeast two-hybrid assay for the identi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-183356