High titer varicella-zoster immune globulin for intravenous admi

Drug – bio-affecting and body treating compositions – Lymphokine

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424 85, 424 89, 424101, 530387, 530388, 530389, 530390, 530391, 530830, A61K 3925

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047175648

ABSTRACT:
Normal plasma from donors who have not been vaccinated with a varicella-zoster vaccine can be screened for higher than normal titers of naturally occurring antibody to varicella-zoster virus. Those plasmas with high titers of such antibody can be pooled and fractionated to give hyperimmune globulin. The product may be treated to render it suitable for intravenous injection. Patients with varicella-zoster infection or at risk to such infection, may receive the present product to raise serum titers of varicella-zoster antibody.

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J. Amer-Med., ASSN-251, (11), 1401, 1405, 1409, 1413, (1984), Immunization Practices Advisory Commission.

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