Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1986-05-05
1989-01-31
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Lymphokine
424 858, 514387, A61K 3940
Patent
active
048014508
ABSTRACT:
Normal plasma from donors who have not been vaccinated with a P seudomonas vaccine or had a Pseudomonas infection can be screened for higher than normal titers of naturally occurring antibody to four or, preferably, two of seven Fisher Immunotypes of Pseudomonas. Those plasmas with higher titers of such antibody can be pooled and fractionated to give hyperimmune serum globulin having high titers of antibody against all seven Fisher Immunotypes. The product may be treated to render it intravenously injectable and the so-prepared material is effective in treating patients with Pseudomonas infection. Also disclosed is a novel antibody preparation including minimum titers of the seven Fisher Immunotypes.
REFERENCES:
patent: 2793203 (1951-05-01), Schultze et al.
patent: 4027010 (1975-04-01), Kiseler et al.
patent: 4120950 (1978-10-01), Homna
patent: 4285936 (1981-08-01), Peer et al.
patent: 4482483 (1984-11-01), Curry et al.
Collins Michael S.
Roby Robert E.
Giblin James A.
Hazel Blondel
Miles Laboratories Inc.
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