Heat exchange – With timer – programmer – time delay – or condition responsive... – Having heating and cooling capability
Patent
1992-10-13
1997-02-11
Ford, John K,
Heat exchange
With timer, programmer, time delay, or condition responsive...
Having heating and cooling capability
422 67, 422109, 422116, 165 64, 165168, 4352851, 4352861, 4352884, 935 87, 935 88, F25B 2900
Patent
active
056011415
ABSTRACT:
A batch thermal cycler for large numbers of biological or chemical samples uses n modules each in good thermal contact with the samples, but substantially isolated from one another, thermally and functionally. Each module carries samples on an upper sample plate. The module has a temperature sensor adjacent the samples, an electrical resistance heating element, and a circulating fluid heat exchanger for step cooling. Heating occurs at a point generally between the samples and the source of the cooling. The modules are individually replaceable. O-rings automatically seal fluid and electrical interfaces. An electrical controller has n simultaneous channels that provide closed loop control of the electrical power to each module. As a method, the invention includes at least one modular temperature zone where the temperature is sensed at a point adjacent the samples in that zone. The samples are heated adjacent the sample plate. Cooling is by a step change. The cooling overshoots a set lower temperature. A small, well-controlled heating corrects the overshoot.
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Christopher Anthony J.
Gordon Steven J.
Ford John K
Intelligent Automation Systems, Inc.
Manus, Esq. Peter J.
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