High throughput screening of gene function using libraries...

Details High throughput screening of gene function using libraries... High throughput screening of gene function using libraries...

2006-04-18

2006-04-18

Ketter, James (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S235100

Reexamination Certificate

active

07029848

ABSTRACT:
Novel means and methods for their use are provided to determine the function of the product(s) of one or more sample nucleic acids. The sample nucleic acids are synthetic oligonucleotides, DNA, or cDNA and encode polypeptides, antisense nucleic acids, or GSEs. The sample nucleic acids are expressed in a host by a vehicle to alter at least one phenotype of the host. The altered phenotype(s) is/are identified as a means to assign a biological function to the product(s) encoded by the sample nucleic acid(s).

REFERENCES:
patent: 4405712 (1983-09-01), Vande Woude et al.
patent: 4497796 (1985-02-01), Salser et al.
patent: 4727028 (1988-02-01), Santerre et al.
patent: 4740463 (1988-04-01), Weinberg et al.
patent: 5190931 (1993-03-01), Inouye
patent: 5208149 (1993-05-01), Inouye
patent: 5518913 (1996-05-01), Massie et al.
patent: 5837511 (1998-11-01), Falck-Pedersen et al.
patent: 5994106 (1999-11-01), Kovesdi et al.
patent: 5994128 (1999-11-01), Fallaux et al.
patent: 6033908 (2000-03-01), Bout et al.
patent: 6040174 (2000-03-01), Imler et al.
patent: 6057427 (2000-05-01), Smith et al.
patent: 6110735 (2000-08-01), Chartier et al.
patent: 6197502 (2001-03-01), Renner et al.
patent: A-28533/95 (1996-03-01), None
patent: 2053187 (1993-04-01), None
patent: 2117668 (1995-09-01), None
patent: 2117669 (1995-09-01), None
patent: 0 707 071 (1996-04-01), None
patent: 0 955 373 (1999-11-01), None
patent: 0 955 373 (1999-11-01), None
patent: 2 707 664 (1995-01-01), None
patent: WO 94/12648 (1984-06-01), None
patent: WO 94/12649 (1994-08-01), None
patent: WO 94/28152 (1994-12-01), None
patent: WO 95/02697 (1995-01-01), None
patent: WO 95/34671 (1995-12-01), None
patent: WO 96/17070 (1996-06-01), None
patent: WO 97/00326 (1997-01-01), None
patent: WO97/27212 (1997-07-01), None
patent: WO97/27213 (1997-07-01), None
patent: WO 97/27213 (1997-07-01), None
patent: WO99/32618 (1999-07-01), None
“Restricted Changes in the Adenovirus DNA-Binding Protein That Lead to Extended Host Range or Temperature-Sensitive Phenotypes” by D.E. Brough, S.A. Rice, S. Sell and D.F. Kelessig—Journal of Virology, Jul. 1985, pp. 206-212.
“Multiplication of Viruses—An Overview” by B. Rolzman—Virology, Second Edition 1990—pp. 28, 29, 87, & 88.
“Ablation of E2A in Recombinant Adenoviruses Improves Transgene Persistence and Decreases Inflammatory Response in Mouse Liver” by J.F. Engelhard, X. Ye, B. Doranz and J.M. Wilson—Proc. Nat. Acad. Sci. USA vol. 91, pp. 6196-6200.
Hall et al.,Genome Research(1996) 6: 781-790.
Jayawickreme and Kost,Current Opinion in Biotechnology(1997) 8: 629-634.
Stein et al.,Nucleic Acids Research(1997) 25: 2598-2602.
Hall et al., “An Approach to High-throughput Genotyping”,Genome Research, 6:781-790, 1996.
Jayawickreme et al., “Gene exprossion systems in the development of high-throughput screens”,Current Opinion in Biotechnology, 8:629-634, 1997.
von Steih et al., “A high throughput screening for rarely transcribed differentially expressed genes”,INucleic Acids Research, vol. 25, No. 13, pp. 2598-2602, 1997.
D.E. Brough, S.A. Rice, S. Sell and D.F. Kelessig. Restricted Changes in the Adenovirus DNA-Binding Protein That Lead to Extended Host Range of Temperature-Sensitive Phenotypes. (Jul. 1985),Journal of Virology, 206-212.
B. Roizman. Multiplication of Viruses—An Overview, (1990),Virology, Second Edition pp. 28, 29, 87, & 89.
J.F. Engelhard, X. Ya, B. Doranz and J.M. Wilson. Ablution of E2A in Recombinant Adenoviruses Improves Transgene Persistence and Decreases Inflammatory Responses In Mouse Liver. (1994)Proc. Nat. Acad. Sci. USA 91, 6196-6200.
Shepherd et al., “Preparation and screening of an arrayed human genomic library generated with the P1 cloning system,”Proc. Natl. Acad. Sci. USA, vol. 91, pp. 2629-2633 (Mar. 1994)†.
Woon et al., “Construction and characterization of a 10-fold genome equivalent Rat P1-derived artificial chromosome library,”Genomics, vol. 50, pp. 306-316 (1998)†.
Crouzet et al.,Proc. Natl. Acad. Sci. USA, vol. 94, pp. 1414-1419 (1997).
Vogelstein et al.,Proc. Natl. Acad. Sci. USA, vol. 95, pp. 2509-2514 (1998).
Davis et al.,Gene Therapy, vol. 5, pp. 1148-1152 (1998).
Ketner et al.,Proc. Natl. Acad. Sci. USA, vol. 91, pp. 6186-6190 (1994).
Okada et al.,Nucleic Acids Research, vol. 26, No. 8, pp. 1947-1950 (1998).
Chartier et al.,J. Virology, vol. 70, pp. 4805-4810 (1996).
Fu et al.,Human Gene Therapy, vol. 8, pp. 1321-1330 (1997).
Tashiro et al.,Human Gene Therapy, vol. 10, pp. 1845-1852 (1999).
Bett et al.,Proc. Natl. Acad. Sci. USA, vol. 91, pp. 8802-8806 (1994).
IIe et al.,Proc. Natl. Acad. Sci. USA, vol. 95, pp. 2509-2514 (1998).
Vollmer et al., “Efficient cloning of genes of Neurospora crassa,”Proc. Natl. Acad. Sci. USA, vol. 83, pp. 4869-4873 (Jul. 1986).

Affiliated with

Also associated with

Rating

High throughput screening of gene function using libraries... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High throughput screening of gene function using libraries..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High throughput screening of gene function using libraries... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3555698