Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-03-29
2005-03-29
Kemmerer, Elizabeth (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S007920, C530S350000
Reexamination Certificate
active
06872538
ABSTRACT:
The present invention is related to a diagnostic an/or dosage method of an agonist and/or an antagonist and/or a modulator for a calcium-coupled receptor and/or channel and/or any other calcium-coupled protein, comprising the following successive steps: disposing the agonist and/or the antagonist and/or the modulator upon a solid support; Incubating one or more cell(s) expressing apoaequorin and said calcium-coupled receptor with coelenterazine in order to reconstitute an active aequorin in said cell(s). The present invention is also related to the diagnostic and/or dosage device intended for the method according to the invention.
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Detheux Michel
Dupriez Vincent
Parmentier Marc
Euroscreen s.a.
Kemmerer Elizabeth
Palmer & Dodge LLP
Wegert Sandra
Williams Kathleen M.
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