High throughput method and system for screening candidate...

Details High throughput method and system for screening candidate... High throughput method and system for screening candidate...

2007-02-13

2007-02-13

Redding, David (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Mutation or genetic engineering apparatus

C435S288400, C435S288700, C204S403010, C204S403030

Reexamination Certificate

active

10770861

ABSTRACT:
Drug candidate screening methods are applied to discover compounds with activity against ion channel targets. The method may include modulating the transmembrane potential of host cells in a plurality of sample wells with a repetitive application of electric fields so as to set the transmembrane potential to a level corresponding to a pre-selected voltage dependent state of a target ion channel.

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