High-throughput-assay with high sensitivity for measuring of...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007720

Reexamination Certificate

active

10931161

ABSTRACT:
The present invention relates to an assay for determining the activity of a G-Protein-Coupled Receptor specific protein kinase by means of an amplified luminescent proximity homo homogenous assay.

REFERENCES:
patent: 6203994 (2001-03-01), Epps et al.
patent: WO 02/22882 (2002-03-01), None
Gray et al. Nonradioactive Methods for the Assay of Phosphoinositide 3-Kinases and Phosphoinositide Phosphatases and Selective Detection of Signaling Lipids in Cell and Tissue Extracts; Analytical Biochemistry, vol. 313 (2003) pp. 234-345.
AlphaScreen Technical Support: AlphaScreen Technology Application Note ASC-001; Principles of Alphascreen (2001), www.packardbioscience.com.
B. Pollok-Kopp et al., Analysis of Ligand-simulated CC Chemokine Receptor 5 (CCR5) Phosphorylation in Intact Cells Using Phosphite-specific Antibodies, Journal of Biological Chemistry, vol. 278, No. 4, Jan. 24, 2003, pp. 2190-2198.
C. Bieri et al., Micropatterned immobilization of a G protein-coupled receptor and direct detection of G protein activation, Nature Biology, vol. 17, Nov. 1999, pp. 1105-1108.
J. Peppard et al., Development of a High-Throughput Assay for Inhibitors of Aggrecan Cleavage Using Luminescent Oxygen Channeling (AlphaScreen), Journal of Biomolecular Screening, vol. 8, No. 2, 2003, pp. 149-156.
M.A. Sills et al., Comparison of Assay Technologies for a Tyrosine Kinase Assay Generates Different Results in High Throughput Screening, Journal of Biomolecular Screening, vol. 7, No. 3, 2002, pp. 191-214.
N. Rouleau et al., Development of a Versatile Platform for Nuclear Receptor Screening Using AlphaScreen, Journal of Biomolecular Screening, vol. 8, No. 2, 2003, pp. 191-197.
X. Wu et al., Comparison of Assay Technologies for a Nuclear Receptor Assay Screen Reveals Differences in the Sets of Identified Functional Antagonists, Journal of Biomolecular Screening, vol. 8, No. 4, 2003, pp. 381-392.
Y. Li et al., Homogeneous assays for adenosine 5′-monophosphate-activated protein kinase, Analytical Biochemistry, vol. 321, 2003, pp. 151-156.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

High-throughput-assay with high sensitivity for measuring of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with High-throughput-assay with high sensitivity for measuring of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High-throughput-assay with high sensitivity for measuring of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3857598

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.