High surface area support having bound latex particles containin

Details High surface area support having bound latex particles containin High surface area support having bound latex particles containin

1992-12-14

1999-11-02

Naff, David M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

424 946, 424 9463, 424 9461, 435 41, 435176, 435177, 435180, 4352625, 436524, 436531, 514 2, 530333, 530402, 530413, 530811, 530815, A61K 3843, C12N 1114, C07K 1714, G01N 33551

Patent

active

059765275

ABSTRACT:
A high surface area system is provided with latex particles for immobilization of substances containing nucleophilic groups. The high surface area system is formed by aggregating the latex particles or by bonding the latex particles to a porous support of high surface area. The latex particles contain groups such as oxirane groups that react with the nucleophilic groups. The substances containing nucleophilic groups may be enzymes or proteins such as albumin, immunoglobulins, blood-clotting factors, cell-membrane proteins or peptide hormones. The high surface area system may be used as a sorbent in removing pollutants, as a stationary phase in organic synthesis such as peptide synthesis, and in the therapeutic treatment of a patient.

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