Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Reexamination Certificate
2006-09-19
2006-09-19
Fortuna, Ana (Department: 1723)
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
C210S645000, C210S321750, C210S321770, C210S321860
Reexamination Certificate
active
07108791
ABSTRACT:
The present invention provides a high-resolution membrane-based method for removing a virus from a manufactured protein-containing solution, the method being particularly characterized by its capacity to be performed quickly (i.e., as measured by flux) and efficiently (i.e., as measured by log reduction value, LRV). Towards such results, the present invention employs a plurality (i.e., greater than 2) of interfacially-contiguous asymmetric ultrafiltration membranes, the foremost of which is oriented with its “tight side” facing downstream. The present invention also provides a filtration capsule, useful in the conduct of the method, comprising a pleated tube formed of three interfacially-contiguous asymmetric ultrafiltration membranes.
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Kazan Greg
Tkacik Gabriel
Fortuna Ana
Millipore Corporation
Nields & Lemack
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