High-resolution spectral signature of human arterial plaque

Details High-resolution spectral signature of human arterial plaque High-resolution spectral signature of human arterial plaque

1987-11-03

1990-07-10

Rosenbaum, C. Fred

Surgery

Truss

Pad

A61B 5055

Patent

active

049400550

ABSTRACT:
Noninvasive method of identifying and quantifying constituents of arterial plaque, comprising subjecting arterial walls to proton NMR spectroscopy or magnetic resonance imaging and looking for sharp spectral lines indicative of the accumulation of lipids within the walls of human arterial blood vessels, and detecting early changes to arterial walls due to atherogenesis. Also this method can be used to obtain information regarding chemical composition of atheroma in situ comprising subjecting an aortic wall to NMR spectroscopy or magnetic resonance imaging and observing spectral peaks indicative of accumulation of lipids within the aortic wall. Magnetic resonance imaging may also be used for this noninvasive method of diagnosing and monitoring atherosclerosis.

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