Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2008-01-24
2011-11-15
Le, Long V (Department: 3768)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S459000, C600S509000, C600S544000, C600S546000
Reexamination Certificate
active
08057390
ABSTRACT:
A current source density mapping system includes an ultrasound transducer emitting an ultrasound wave traveling along an ultrasound beam directed at a mapping field in a region of living tissue and an ultrasound pulser delivering a transmit pulse to said ultrasound transducer. The system includes a timing device producing controlled excitation of the transmit pulse; a plurality of recording electrodes positioned in contact with the living tissue detecting an acoustoelectric voltage signal generated at a bioelectric current source and within a focal zone of said ultrasound beam. An amplifier operatively connected to the recording electrodes amplifying the acoustoelectric voltage signal at a predetermined gain; and an analyzing component comprising a digitizer, a sampling device, a signal processor and a display unit operatively connected to the amplifier determining the location of the bioelectric current source by analyzing the acoustoelectric voltage signal detected by the recording electrodes in response to an interaction between the ultrasound wave and the presence of a current source in the mapping field.
REFERENCES:
patent: 6584345 (2003-06-01), Govari
patent: 2007/0299353 (2007-12-01), Harlev et al.
Olafsson et al., “Electric Current Mapping using the Acousto-Electric Effect”, Proc. of SPIE, vol. 6147, Mar. 2006, pp. 1-11.
Zhang et al., “Acousto-electric Tomography”, Proceedings of SPIE, vol. 5320, Bellingham, WA, 2004.
O'Donnell Matthew
Olafsson Ragnar
Witte Russell S.
Fernandez Katherine
Harness & Dickey & Pierce P.L.C.
Le Long V
The Regents of The University of Michigan
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