Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-06-06
1990-12-11
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530412, 530415, 530418, 530419, C07K 324, C07K 328, C07K 318
Patent
active
049772465
ABSTRACT:
Disclosed is a method of recovery of antihemophilic factor (AHF) from human plasma by precipitation with citric acid, sodium citrate, or potassium citrate.
REFERENCES:
patent: 2867567 (1959-01-01), Bidwell
patent: 3920625 (1975-11-01), Andersson et al.
patent: 3973002 (1976-08-01), Hagan et al.
patent: 4383989 (1983-05-01), Rock
Brinkhous et al., "A New High--Potency Glycine--Precipitated Anti--Hemophilic Factor (AHF) Concentrate", (JAMA, Aug. 26, 1988, vol. 205, No. 9).
Newman et al., "Methods for the Production of Clinically Effective Intermediate-- and High--Purity Factor VIII Concentrates", (British Journal of Haemotology, 1971, 21, pp. 1-20).
Hrinda Michael E.
Lee Ted C. K.
Balogh Imre (Jim)
Furman Keith C.
Moskowitz Margaret
Nicholson James A.
Rorer Pharmaceutical Corporation
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