High-Q pulsed fragmentation in ion traps

Details High-Q pulsed fragmentation in ion traps High-Q pulsed fragmentation in ion traps

2006-09-05

2006-09-05

Nguyen, Kiet T. (Department: 2881)

Radiant energy

Ionic separation or analysis

Cyclically varying ion selecting field means

C250S290000

Reexamination Certificate

active

07102129

ABSTRACT:
Rapid and efficient fragmentation of ions in an ion trap for MS/MS analysis is achieved by a pulsed fragmentation technique. Ions of interest are placed at an elevated value of Q and subjected to a relatively high amplitude, short-duration resonance excitation pulse to cause the ions to undergo collision-induced fragmentation. The Q value of the ions of interest is then rapidly reduced, thereby decreasing the low-mass cutoff and allowing retention and subsequent analysis of low-mass ion fragments.

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