High-purity large-scale preparation of stannsoporfin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S145000

Reexamination Certificate

active

07960371

ABSTRACT:
Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.

REFERENCES:
patent: 4619923 (1986-10-01), Kappas et al.
patent: 4657902 (1987-04-01), Kappas et al.
patent: 4668670 (1987-05-01), Rideout et al.
patent: 4684637 (1987-08-01), Kappas et al.
patent: 4692439 (1987-09-01), Rideout et al.
patent: 4692440 (1987-09-01), Kappas et al.
patent: 4708964 (1987-11-01), Allen
patent: 4782049 (1988-11-01), Kappas et al.
patent: 4831024 (1989-05-01), Vreman et al.
patent: 4861876 (1989-08-01), Kessel
patent: 4900871 (1990-02-01), Ellis, Jr. et al.
patent: 5010073 (1991-04-01), Kappas et al.
patent: 5062775 (1991-11-01), Orth
patent: 5081115 (1992-01-01), Vreman et al.
patent: 5162313 (1992-11-01), Kappas et al.
patent: 5192757 (1993-03-01), Johnson et al.
patent: 5223494 (1993-06-01), Kappas et al.
patent: 5275801 (1994-01-01), Niedballa et al.
patent: 5371199 (1994-12-01), Therien et al.
patent: 5493017 (1996-02-01), Therien et al.
patent: 5817830 (1998-10-01), Therien et al.
patent: 5883246 (1999-03-01), Brückner et al.
patent: 5886173 (1999-03-01), Hemmi et al.
patent: 5889181 (1999-03-01), Kudrevich et al.
patent: 5912341 (1999-06-01), Hoffman et al.
patent: 5929064 (1999-07-01), Goel et al.
patent: 5955603 (1999-09-01), Therien et al.
patent: 5973141 (1999-10-01), Robinson et al.
patent: 5990363 (1999-11-01), Wijesekera et al.
patent: 6004530 (1999-12-01), Sagner et al.
patent: 6066333 (2000-05-01), Willis et al.
patent: 6114321 (2000-09-01), Platzek et al.
patent: 6124452 (2000-09-01), DiMagno
patent: 6177561 (2001-01-01), Sinn et al.
patent: 6194566 (2001-02-01), Platzek et al.
patent: 6235895 (2001-05-01), McEwan et al.
patent: 6420553 (2002-07-01), Inoue et al.
patent: 6462192 (2002-10-01), Robinson et al.
patent: 6818763 (2004-11-01), Vukovich et al.
patent: 7375216 (2008-05-01), Vukovich et al.
patent: 2003/0100752 (2003-05-01), Robinson
patent: 2003/0225264 (2003-12-01), Vukovich et al.
patent: 2004/0097481 (2004-05-01), Levinson et al.
patent: 2004/0210048 (2004-10-01), Vukovich et al.
patent: 2006/0222668 (2006-10-01), Drummond et al.
patent: 2006/0222669 (2006-10-01), Drummond et al.
patent: 2008/0113955 (2008-05-01), Levinson et al.
patent: 2008/0154033 (2008-06-01), Vukovich et al.
patent: 2008/0261939 (2008-10-01), Drummond et al.
patent: 2448570 (2002-12-01), None
patent: 0199888 (1986-11-01), None
patent: 58-501130 (1983-07-01), None
patent: 1-501627 (1989-08-01), None
patent: WO-89/02269 (1989-03-01), None
patent: WO 91/04667 (1991-04-01), None
patent: WO-94/28906 (1994-12-01), None
patent: WO 97/05152 (1997-02-01), None
patent: WO 01/68099 (2001-09-01), None
patent: WO-03/101999 (2003-12-01), None
patent: WO-03/101999 (2003-12-01), None
patent: WO2004-045546 (2004-06-01), None
patent: WO-2004/045546 (2004-06-01), None
patent: WO-2004/045546 (2004-06-01), None
patent: WO-2005/103056 (2005-11-01), None
patent: WO-2005/103056 (2005-11-01), None
patent: WO 2006/107806 (2006-10-01), None
patent: WO 2006/107806 (2006-10-01), None
patent: WO 2008/045377 (2008-04-01), None
patent: WO 2008/045377 (2008-04-01), None
patent: WO 2008/045378 (2008-04-01), None
patent: WO 2008/045378 (2008-04-01), None
Baker, E.W. et al. (Aug. 1964). “The Preparation of Mesoporphyrin IX and Etioporphyrin III,”Analytical Biochemistry8(4):512-518.
Bauer, J. et al. (1988). “Stability-Indicating High Performance Liquid Chromatographic Analysis of Tin Protoporphyrin and Other Free Acid Metalloporphyrins,”Journal of Chromatography445:429-432.
Cowan, J.A. et al. (May 31, 1989). “Synthesis and Properties of Metal-Substituted Myoglobins,”Inorganic Chemistry28(11):2074-2078.
Delaney, J.K. et al. (Apr. 1988). “Photophysical Properties of Sn-Porphyrins: Potential Clinical Implications,”Pediatrics81(4):498-504.
Ellfolk, N. et al. (1969). “Separation of Porphyrins by Multiple Liquid-Liquid Partition,”Acta. Chem. Scand. 23(3 part I):846-858.
Kappas, A. et al. (Apr. 1995). “Direct Comparison of Sn-Mesoporphyrin, An Inhibitor of Bilirubin Production, and Phototherapy in Controlling Hyperbilirubinemia in Term and Near-Term Newborns,”Pediatrics95(4):468-474.
Sugihara, J.M. et al. (Nov. 1964). “Determination of Vanadyl Porphyrins by Demetalation with Hydrogen Bromide-Formic Acid,”Analytical Chemistry36(12):2374-2376.
Taylor, J.F. (Sep. 1, 1940). “Metalloporphyrins. II. Cobalt and Manganese Mesoporphyrins in Coordination with Nitrogenous Bases,”Journal of Biological Chemistry135(2):569-595.
U.S Appl. No. 11/867,581, filed Oct. 4, 2007, by Drummond et al. (not attached).
Valaes, T. et al. (Jan. 1994). “Control of Jaundice in Preterm Newborns by an Inhibitor of Bilirubin Production: Studies With Tin-Mesoporphyrin,” Pediatrics 93(1):1-11.
Bauer et al. “Pharmazeutische Technologie” 1993published by George Thieme Verlag Stuttgart(New York) 4th Ed. pp. 225-227.
Bettelheim et al. “Chapter 8. Proteins” 1998,General Organic&Biochemistry, 5thEd. p. 596.
Bhutani et al. “Randomized Placebo-Controlled Clinical Trial of Stannsoporfin (Sn-MP) to Prevent Severe Hyperbillirubinemia in Term and Near-Term Infants” Apr. 2004Pediatric ResearchAbstract No. 2542.
Breslow et al. “Biochemical Properties of the Heme Oxygenase Inhibitor, Sn-Protoporphyrin” Mar. 5, 1986,The Journal of Biological Chemistry261(7):3135-3141.
Corwin et al. “A Synthetic Ferroporphyrin Complex That Is Passive to Oxygen” Aug.-Dec. 1946Journal of the American Chemical Society68:2473-2478.
Drummond et al. “Reduction of the C2and C4Vinyl groups of Sn-Protoporphyrin to Form Sn-Mesoporphyrin Markedly Enhances the Ability of the Metalloporphyrin to Inhibit in Vivo Heme Catabolism” May 15, 1987,Archives of Biochemistry and Biophysics255(1):64-74.
Drummond et al. “An Experimental Model of Postnatal Jaundice in the Suckling Rat, Suppression of Induced Hyperbillirubinemia by Sn-Protoprophyrin” Jul. 1984,J. Clin. Invest. 74:142-149.
Drummond et al. “Prevention of neonatal hyperbillirubinemia by tin Protoporphyrin IX, a potent competitive inhibitor of heme oxidation” Oct. 1981,Proc. Natl. Acad. Sci. USA78(10):6466-6470.
Drummond et al. “Chemoprevention of Severe Neonatal Hyperbillirubinemia” Oct. 2004,Seminars in Perinatology28(5):365-368.
Drummond “Control of Heme Metabolism by Synthetic Metalloporphyrins” 1987,Annals of New York Academy of Sciences514:87-95.
Galbraith et al. “Pharmacokinetics of Tin-Mesoporphyrin in Man and the Effects of Tin-Chelated Porphyrins of Hyperexcretion of Heme Pathway Precursors in Patients with Acute Inducible Porphyria” Jun. 1989,Hepatology9(6):882-888.
Hamori et al. “Suppression of Carbon Monoxide Excretion by Zinc Mesoporphyrin in Adult Wistar Rats: Evidence for Potent in Vivo Inhibition of Billirubin Production” Oct. 1988,Research Communications in Chemical Pathology and Pharmacology62(1):41-48.
Hansen “Kernicterus in Term and Near-Term Infants—The Specter Walks Again” Oct. 2000, Acta Pediatrica 89(10):1155-1157.
International Search Report mailed May 26, 2004 for PCT Patent Application No. PCT/US 03/36885 filed Nov. 18, 2003, two pages.
International Search Report mailed Jun. 21, 2004 for PCT Patent Application No. PCT/US 03/17426 field Jun. 3, 2003, two pages.
International Search Report mailed Feb. 9, 2007 for PCT Patent Application No. PCT/US 04/39240 filed Nov. 24, 2004, two pages.
International Search Report mailed May 24, 2007 for PCT Application No. PCT/US 06/12185 filed Mar. 31, 2006, three pages.
International Search Report mailed Mar. 27, 2008 for PCT Patent Application No. PCT/US07/21485 filed Oct. 4, 2007, three pages.
International Search Report mailed Apr. 3, 2008 for PCT Patent Applicatoin No. PCT/US 07/021486 filed on Apr. 10, 2007, 5 pages.
Kaplan et al. “Determination of Isosmolar Blood Anticoagulant Solutions by the Fr

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