High pressure MS/MS system

Details High pressure MS/MS system High pressure MS/MS system

1998-04-28

2000-07-25

Berman, Jack

Radiant energy

Ionic separation or analysis

Methods

250288, 250292, H01J 4942

Patent

active

06093929&

ABSTRACT:
A mass spectrometer system in which ions are mass selected in an RF-only quadrupole at relatively high pressure (1 to 7 torr) using FNF or SWIFT, and are then fragmented in a following collision cell which is in the same vacuum chamber, thus reducing pumping needs. The fragments can be mass analyzed in any desired way, including by another RF-only quadrupole in the same vacuum chamber and also using FNF or SWIFT. Triple MS can be performed in the same way.

REFERENCES:
patent: 3335225 (1967-08-01), Campanella et al.
patent: 4963736 (1990-10-01), Douglas et al.
patent: 5187365 (1993-02-01), Kelley
patent: 5248875 (1993-09-01), Douglas et al.
Thomson, Bruce A. et al, "Improved Collisionally Activated Dissociation Efficiency and Mass Resolution on a Triple Quadrupole Mass Spectrometer System", Analytical Chemistry, vol. 67, No. 10, May 15, 1995, pp. 1696-1704.

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