Agitating – Having specified feed means – Adjustable mixing ratio control
Patent
1982-09-08
1985-03-26
Coe, Philip R.
Agitating
Having specified feed means
Adjustable mixing ratio control
366177, 366339, 366341, B01F 504, B01F 1310, B01F 1502
Patent
active
045069875
ABSTRACT:
A gradient mixer which effects the continuous mixing of any two miscible solvents without excessive decay or dispersion of the resultant isocratic effluent or of a linear or exponential gradient. The two solvents are fed under low or high pressure by means of two high performance liquid chromatographic pumps. The mixer comprises a series of ultra-low dead volume stainless steel tubes and low dead volume chambers. The two solvent streams impinge head-on at high fluxes. This initial nonhomogeneous mixture is then passed through a chamber packed with spirally-wound wires which cause turbulent mixing thereby homogenizing the mixture with minimum "band-broadening".
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"Rotating Flow Mixing Device for Post Column Reaction in High Performance Liquid Chromatography", Shin-ichiro Kobayashi and Kazuhiro Imai, Anal. Chem., 52, 1548, (1980).
Daughton Christian G.
Sakaji Richard H.
Carnahan L. E.
Coe Philip R.
Gaither Roger S.
Hightower Judson R.
The United States of America as represented by the United States
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