Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Patent
1983-09-27
1987-04-07
Richman, Barry S.
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
436 94, 436128, 436131, 436132, 436140, 436161, 436111, G01N 2175, G01N 3002, G01N 3300
Patent
active
046561412
ABSTRACT:
A process for detecting the presence of trace amounts of non-fluorescent soluble compounds each having at least one labile hydrogen atom in a carrier solution by adding a non-fluorescent quinone which is reducible to a fluorescent hydroquinone, and irradiating the resulting solution in the absence of oxygen with light of sufficient energy to cause the quinone to be reduced to a hydroquinone. The invention further provides a novel photochemical reactor--recording fluorometer combination and carrier liquid--quinone solution for performing the analysis.
REFERENCES:
Birks et al., "Photochemical Reaction Detection in HPLC", Trends in Anal. Chem., vol. 1, No. 15, 1982, pp. 361-367.
Wilkinson, "Transfer of Triplet State Energy and the Chemistry of Excited States", J. Phys. Chem., 66:2569 (1962).
Elliot et al., J. Phy. Chem., vol. 82, No. 4, 1978, A CIDEP Study of the Photoreduction of Quinones in the Presence of Phenols and 2-Propanol.
Gandelman et al., J. Chrom. 242 (1982) pp. 22-31.
Brinkman et al., J. Chrom. 217 (1981) pp. 463-471.
Birks John W.
Gandelman Mitchell S.
Delahunty C. M.
Richman Barry S.
Shimei Barbara A.
University Patents Inc.
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